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Nonbenzodiazepine pharmacodynamics are almost entirely the same as benzodiazepine drugs and therefore employ similar benefits, side-effects, and risks. However, nonbenzodiazepines have dissimilar or entirely different chemical structures and are therefore unrelated to benzodiazepines on a molecular level.



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They are considered to be minor tranquilizers, and are often used before certain medical procedures; especially endoscopies and dental work. Sometimes they are used to neutralize the anxiety-related symptoms that may accompany the initial use of selective serotonin reuptake inhibitors SSRIs and other antidepressants.



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Organophosphate OP -nerve agent poisoning may lead to prolonged epileptiform seizure activity, which can result in irreversible neuronal brain damage. A timely and effective control of seizures with pharmacological agents can minimize the secondary and long-term neuropathology that may result from this damage.

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With the introduction of chlordiazepoxide Librium and diazepam Valium in the early s, a new era in the treatment of insomnia and anxiety began. The benzodiazepines were more effective and far safer than the older drugs — barbiturates, meprobamate, and glutethimide — that had been prescribed for these purposes.



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Medically reviewed on May 4, by L. Benzodiazepines are a class of medications that work in the central nervous system and are used for a variety of medical conditions.

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